생물정보학 세미나 공지

서울대학교 생물정보연구소 및 생물정보학 협동과정 공동 주최로 특별 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

일시: 2012년 6월 4일(월) 11:00
연사: Andreas C. Kurtz

         (Seoul National University, College of Veterinary Medicine, Seoul, Republic of Korea) 장소: 25동 411호

Title: CellFinder

       : An Integrated Stem Cell and Developmental Biology platform and data repository

 

Abstract:

Cells as the building blocks of tissues, organs and organisms are a natural key unit for data integration. The central importance of cells in the establishment, maintenance and regulation of tissues and organs has long been recognized. Hence, an enormous body of cell related data has been accumulated, including histopathological, cell-anatomical, substructural, proteomics and genomics as well as functional data. Many of these data are only available from in vivo analysis, while others have been derived from in vitro analysis of cultured cell types. The body of cell-related information on the single cell level is rapidly increasing, however, resources that comprehend the available data on specific cells are not available and complicated by the diversity of data source, context and format.

CellFinder aims at mapping information related to the cell unit as a basis for increased comparability of data, cells and their relation to more complex systems. To organize the data stored in CellFinder we have developed a novel ontology that allows the annotation of data from the organ down to the single cell level and mapping of homologous entities between species. Furthermore this ontology allows mapping of developmental data and cell lineage differentiation. Existing taxonomies such as the gene ontology (GO) or Foundational Model of Anatomy (FMA) are used for data annotation. Here, I will present an approach to map stem cell related data in CellFinder and discuss the use of CellFinder for systemic modelling of organisms.

Current work concentrates on the integration of existing cell biology datasets to assimilate the diverse dimensions of molecular, functional, anatomical and cyto-histological, as well as auxiliary data.

 

Professional Career - Academic

Since 2009 : Professor, Seoul National University, College of Veterinary Medicine

2006-now : PI, Laboratory of Stem Cell Research and Knowledge Management,

                      Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin

2003-2006 : Head, National Authority for Embryonic Stem Cell Research and Stem Cell Research Laboratory,

                       Robert-Koch-Institute, Berlin

2003-2006 : Adjunct Associate Professor for Neurosurgery, Harvard University, Cambridge, USA

                       PI, Nervous system tumor research and therapy development

2000-2003 : Assistant Professor for Neurosurgery at Harvard Medical School / Massachusetts General Hospital,

                       Cambridge/Boston, USA

1995-2000 : Assistant Professor for Pharmacology and Neurosurgery, Georgetown University, Washington DC, USA

1993-1995 : Guest Scientist at NIH/NIMH, Bethesda, USA

1990-1992 : Postdoctoral Fellow at NIH/NIMH Bethesda, USA and Ludwig Institute for Cancer Research,

                      Uppsala, Sweden

1985-1990 : Staff Scientist, Central Institute for Molecular Biology at the Academy of Sciences of GDR, Berlin-Buch,

                       Germany

 

Professional Career - Industrial

2006-2008 : CSO/CEO Pharmicell Europe GmbH, Berlin, Germany

1999-2001 : CTO/CEO Institute for Genetic Medicine INGENE GmbH, Berlin, Germany

1997-2000 : CEO Genomed Diagnostic GmbH Berlin/ IMMD, Germany

 
Education

1990 : Ph.D. (Genetics, Cell Biology), Academy of Sciences of GDR

1980-1985 : Diploma (Biology/Genetics) Martin Luther University Halle

 

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