생물정보학 세미나 공지

     

 

      

서울대학교 생물정보연구소 및 생물정보학 협동과정 공동 주최로 특별 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

       

일시: 2012년 5월 11일(금) 오후 4시        

연사: 이인석 교수(연세대학교)  

장소: 25동 411호 

       

Title: Network-guided Systems Genetics 

  

Abstract:  

The ultimate goal of biological research is to manipulate traits that are important for medicine, agriculture, and bio-industry. This challenging task first requires good understanding of association between genotype and phenotype. Because of high complexity of genotype as well as phenotype, complexity of the genotype-phenotype association could be even untouchable by combinatorial explosion of the number of possible associations. Therefore, modern genetics needs to be more systematic and predictive. Recently we proposed network-guided approach for genetics of complex traits. First, we construct probabilistic functional gene networks for cells or organisms by benchmarking and integrating heterogeneous multi-omics data that are in general publicly available. Then, using guilt-by-association, and other algorithms of network propagation of known biological information, we predict gene functions, phenotypic effect of loss-of-function, and epistatic interaction. The information can contribute to reconstruction of map between genotype and phenotype. The network-guided genetics method has been effectively applied for various organisms; from simple microbe yeast, to multicellular animal C. elegans, to the reference plant Arabidopsis, to the reference crop rice, and to the human.

      

Bio:  

Professional Experience  

03/2012 – present Associate Professor, Department of Biotechnology, Yonsei University, Seoul, Korea.  

03/2008 – 02/2012 Assistant Professor, Department of Biotechnology, Yonsei University, Seoul, Korea.

 

Education 

01/2003–02/2008 Postdoctoral Work, University of Texas at Austin, TX  

09/1996–12/2002 Ph.D., University of Texas at Austin, TX   

09/1993–05/1996 M.S., Western Illinois University, Macomb, IL  

03/1986–02/1993 B.S. in Biology, Hanyang University, Seoul, Korea

       

서울대학교 생물정보연구소

 

자연과학대학 생물정보학 협동과정 공동주최